Week 339: Case 6

1. Presented by Peter Illei, M.D. and prepared by Wang (Steve) Cheung, M.D., Ph.D.

50 y.o. African American male patient whose chest x- ray performed to confirm placement of a PICC line for intravenous antibiotics showed a large anterior mediastinal mass. Further tests documented a 4 x 7 x 4.5 cm mediastinal mass causing a 90% occlusion of the superior vena cava, as well as associated mediastinal lymphadenopathy, bilateral lung infiltrates and a right lower lobe nodule. Biopsy documented a "malignant thymoma". It was considered to be unresectable so chemotherapy with cisplatin, adriamycin and cytoxan was started in 07/2007. His response to chemotherapy permitted a surgical resection 4 month later.