cases, mediastinum Week 339: Case 6 April 26, 2023 pathadmin 1. Presented by Peter Illei, M.D. and prepared by Wang (Steve) Cheung, M.D., Ph.D.50 y.o. African American male patient whose chest x- ray performed to confirm placement of a PICC line for intravenous antibiotics showed a large anterior mediastinal mass. Further tests documented a 4 x 7 x 4.5 cm mediastinal mass causing a 90% occlusion of the superior vena cava, as well as associated mediastinal lymphadenopathy, bilateral lung infiltrates and a right lower lobe nodule. Biopsy documented a "malignant thymoma". It was considered to be unresectable so chemotherapy with cisplatin, adriamycin and cytoxan was started in 07/2007. His response to chemotherapy permitted a surgical resection 4 month later./images/205086a.jpg/images/205086b.jpg/images/205086c.jpg/images/205086d.jpg/images/205086e.jpgThymic carcinoma (WHO type C thymoma)Invasive thymoma, WHO type B3Hodgkin's lymphoma, nodular sclerosing typeMediastinal large B-cell lymphoma Loading...