cases, gallbladder Week 339: Case 2 April 26, 2023 pathadmin 1. Presented by Peter Illei, M.D. and prepared by Wang (Steve) Cheung, M.D., Ph.D.67 y.o. African American female patient who had a 1-month history of profound jaundice and pruritus and a 15-pound weight loss. She had been treated by the dermatologist and was prescribed Zyrtec, but continued with the pruritus. MRI revealed a mass in the gallbladder and at the bifurcation. Upon opening the gallbladder a 5.0 cm polypoid mass was noted in the fundus.Adenocarcinoma of gallbladder with papillary featuresMetastatic adenocarcinoma of colonHepatocellular carcinomaAdenomyoma of gallbladder 1. Presented by Peter Illei, M.D. and prepared by Wang (Steve) Cheung, M.D., Ph.D.67 y.o. African American female patient who had a 1-month history of profound jaundice and pruritus and a 15-pound weight loss. She had been treated by the dermatologist and was prescribed Zyrtec, but continued with the pruritus. MRI revealed a mass in the gallbladder and at the bifurcation. Upon opening the gallbladder a 5.0 cm polypoid mass was noted in the fundus.